PMID | Allele | Disease | Population | Drug Names | SNP | Class | Sentence |
---|---|---|---|---|---|---|---|
23396243 | HUMAN LEUKOCYTE ANTIGEN (HUMAN LEUKOCYTE ANTIGEN) | hematopoietic stem cell transplantation | NA | NA | NA | unclassified | |
haploidentical hematopoietic stem cell transplantation (hsct) constitutes an important alternative for patients lacking a human leukocyte antigen (hla)-matched donor. | |||||||
23404428 | HLA-CLASS I (HLA CLASS II) | hematopoietic stem cell transplantation | NA | NA | NA | unclassified | |
it is also well established that mismatching of hla class i-encoded kir ligands in the setting of hematopoietic stem cell transplantation leads to allorecognition of leukemic cells by nk cells, which is in line with the concept of missing-self recognition. | |||||||
23430876 | HLA IDENTICAL (HLA-IDENTICAL) | hematopoietic stem cell transplantation | NA | NA | NA | unclassified | |
given her life-threatening course, she underwent allogeneic hematopoietic stem cell transplantation (hsct) from her hla-identical brother, confirmed heterozygous for the c.1133delacg allele. | |||||||
23596045 | NA (NA) | hematopoietic stem cell transplantation | NA | NA | NA | unclassified | |
multiple mismatches at the low expression hla loci dp, dq, and drb3/4/5 associate with adverse outcomes in hematopoietic stem cell transplantation. | |||||||
23596045 | DP (HAPLOTYPE) | hematopoietic stem cell transplantation | NA | NA | NA | unclassified | |
multiple mismatches at the low expression hla loci dp, dq, and drb3/4/5 associate with adverse outcomes in hematopoietic stem cell transplantation. | |||||||
23596045 | NA (NA) | hematopoietic stem cell transplantation | NA | NA | NA | positive | |
a single mismatch in highly expressed hla-a, -b, -c, and -drb1 loci (hel) is associated with worse outcomes in hematopoietic stem cell transplantation, while less is known about the cumulative impact of mismatches in the lesser expressed hla loci drb3/4/5, dq, and dp (lel). | |||||||
23596045 | DP (HAPLOTYPE) | hematopoietic stem cell transplantation | NA | NA | NA | positive | |
a single mismatch in highly expressed hla-a, -b, -c, and -drb1 loci (hel) is associated with worse outcomes in hematopoietic stem cell transplantation, while less is known about the cumulative impact of mismatches in the lesser expressed hla loci drb3/4/5, dq, and dp (lel). | |||||||
23596045 | HLA-A (HLA-A) | hematopoietic stem cell transplantation | NA | NA | NA | positive | |
a single mismatch in highly expressed hla-a, -b, -c, and -drb1 loci (hel) is associated with worse outcomes in hematopoietic stem cell transplantation, while less is known about the cumulative impact of mismatches in the lesser expressed hla loci drb3/4/5, dq, and dp (lel). | |||||||
23596045 | HLA-DRB1 (HLA-DRB1) | hematopoietic stem cell transplantation | NA | NA | NA | positive | |
a single mismatch in highly expressed hla-a, -b, -c, and -drb1 loci (hel) is associated with worse outcomes in hematopoietic stem cell transplantation, while less is known about the cumulative impact of mismatches in the lesser expressed hla loci drb3/4/5, dq, and dp (lel). | |||||||
23619468 | HLA (HLA) | hematopoietic stem cell transplantation | NA | NA | NA | unclassified | |
here we have addressed this issue by studying hla-dp3, a common antigen relevant for functional matching algorithms of unrelated hematopoietic stem cell transplantation (hsct) encoded by two transmembrane (tm) region variants, dpb1(*)03:01 and dpb1(*)104:01. |
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