PMID | Allele | Disease | Population | Drug Names | SNP | Class | Sentence |
---|---|---|---|---|---|---|---|
24712264 | HLA (HLA) | kidney failure | NA | NA | NA | positive+negation | |
there was no significant relationship between nmsc appearance and sex, cause of kidney failure, hla mismatch, blood group as well as rh factor. | |||||||
8863776 | HLA MATCHED (HLA-MATCHED) | immune thrombocytopenic purpuras | Italian | NA | NA | unclassified | |
threonine145/methionine145 dimorphism in platelet glycoprotein (gp) ib alpha defines the human platelet antigen (hpa)-2 system that has been implicated in refractoriness to hla-matched platelet transfusion and in neonatal immune thrombocytopenic purpura.study design and the occurrence of this amino acid dimorphism was investigated in 379 italian blood donors by studying their genomic dna. | |||||||
8871945 | HLA-DR (HLA-DR) | prednisone | NA | colchicine | NA | unclassified | |
NA | |||||||
27802514 | HLA-DR (HLA-DR) | choroidal neovascularization | NA | NA | NA | positive | |
in eyes with neovascular amd, there were significantly more hla-dr+ cells associated with submacular choroidal neovascularization (p = 0.001). | |||||||
9374144 | HUMAN LEUKOCYTE ANTIGEN (HUMAN LEUKOCYTE ANTIGEN) | skin grafting | NA | NA | NA | unclassified | |
cryopreservation of allogeneic skin may be important in the treatment of human leukocyte antigen-mismatch patients with giant nevi, and ace should be applied within 10 days of skin grafting. | |||||||
8908376 | HLA-DR (HLA-DR) | prediabetes | NA | NA | NA | positive | |
these results demonstrate that prediabetes is characterized by persistent elevation of hla-dr+ cd8+ t-cells with the same cytotoxic phenotype as cells predominating in the islet at diagnosis, suggesting that the circulating cells may have a role in the pathogenesis of islet damage. | |||||||
15004204 | DQ8 (HAPLOTYPE) | prediabetes | NA | NA | NA | unclassified | |
hla-dq8-associated t cell responses to the diabetes autoantigen phogrin (ia-2 beta) in human prediabetes. | |||||||
15004204 | DQ8 (HAPLOTYPE) | autoimmune diabetes | NA | NA | NA | positive | |
susceptibility to type 1a autoimmune diabetes is linked to expression of particular mhc class ii molecules, notably hla-dq8 in man and the orthologous i-ag7 in the nonobese diabetic mouse. | |||||||
8912593 | HLA-CLASS I (HLA CLASS II) | skin ulcers | NA | NA | NA | unclassified | |
defective expression of hla class i and cd1a molecules in boy with marfan-like phenotype and deep skin ulcers. | |||||||
8912593 | HLA-CLASS I (HLA CLASS II) | skin ulcers | NA | NA | NA | unclassified | |
it is therefore speculated that a defective expression of cd1a molecules can contribute to the chronic persistence of deep skin ulcers, which have already been reported in association with defective expression of hla class i molecules. |
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