HLA Web Resource for SNPs, Populations, Resources, ADRs, Diseases

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PMID Allele Disease Population Drug Names SNP Class Sentence
24712264 HLA (HLA) kidney failure NA NA NA positive+negation
there was no significant relationship between nmsc appearance and sex, cause of kidney failure, hla mismatch, blood group as well as rh factor.
8863776 HLA MATCHED (HLA-MATCHED) immune thrombocytopenic purpuras Italian NA NA unclassified
threonine145/methionine145 dimorphism in platelet glycoprotein (gp) ib alpha defines the human platelet antigen (hpa)-2 system that has been implicated in refractoriness to hla-matched platelet transfusion and in neonatal immune thrombocytopenic purpura.study design and the occurrence of this amino acid dimorphism was investigated in 379 italian blood donors by studying their genomic dna.
8871945 HLA-DR (HLA-DR) prednisone NA colchicine NA unclassified
NA
27802514 HLA-DR (HLA-DR) choroidal neovascularization NA NA NA positive
in eyes with neovascular amd, there were significantly more hla-dr+ cells associated with submacular choroidal neovascularization (p = 0.001).
9374144 HUMAN LEUKOCYTE ANTIGEN (HUMAN LEUKOCYTE ANTIGEN) skin grafting NA NA NA unclassified
cryopreservation of allogeneic skin may be important in the treatment of human leukocyte antigen-mismatch patients with giant nevi, and ace should be applied within 10 days of skin grafting.
8908376 HLA-DR (HLA-DR) prediabetes NA NA NA positive
these results demonstrate that prediabetes is characterized by persistent elevation of hla-dr+ cd8+ t-cells with the same cytotoxic phenotype as cells predominating in the islet at diagnosis, suggesting that the circulating cells may have a role in the pathogenesis of islet damage.
15004204 DQ8 (HAPLOTYPE) prediabetes NA NA NA unclassified
hla-dq8-associated t cell responses to the diabetes autoantigen phogrin (ia-2 beta) in human prediabetes.
15004204 DQ8 (HAPLOTYPE) autoimmune diabetes NA NA NA positive
susceptibility to type 1a autoimmune diabetes is linked to expression of particular mhc class ii molecules, notably hla-dq8 in man and the orthologous i-ag7 in the nonobese diabetic mouse.
8912593 HLA-CLASS I (HLA CLASS II) skin ulcers NA NA NA unclassified
defective expression of hla class i and cd1a molecules in boy with marfan-like phenotype and deep skin ulcers.
8912593 HLA-CLASS I (HLA CLASS II) skin ulcers NA NA NA unclassified
it is therefore speculated that a defective expression of cd1a molecules can contribute to the chronic persistence of deep skin ulcers, which have already been reported in association with defective expression of hla class i molecules.
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