PMID | Allele | Disease | Population | Drug Names | SNP | Class | Sentence |
---|---|---|---|---|---|---|---|
27325175 | HLA IDENTICAL (HLA-IDENTICAL) | stem cell transplantation | NA | imatinib | NA | negative | |
after two courses of intensification chemotherapy, the patient underwent reduced intensity stem cell transplantation from an hla-identical sibling donor followed by post-transplant imatinib. | |||||||
27492906 | HLA-A*23 | stem cell transplantation | African | NA | NA | unclassified | |
hla-a*23:01:19, a novel variant of hla-a*23:01, discovered in a west african stem cell transplantation patient. | |||||||
27569099 | HLA (HLA) | stem cell transplantation | NA | NA | NA | unclassified | |
the patient underwent allogeneic stem cell transplantation (allo-sct) from hla matched sister and he subsequently achieved complete remission. | |||||||
27570526 | HLA (HLA) | stem cell transplantation | NA | NA | NA | positive | |
more recently, anti-hla immunization was shown to increase the risk of primary graft failure (pgf), a severe complication of ahsct that occurs in 3-4% of matched unrelated donor transplantation and up to 15% in cord blood transplantation and t-cell depleted haplo-identical stem cell transplantation. | |||||||
27570526 | HLA (HLA) | hematopoietic stem cell transplantation | NA | NA | NA | unclassified | |
donor-specific anti-hla antibodies in allogeneic hematopoietic stem cell transplantation. | |||||||
27618304 | HLA MATCHED (HLA-MATCHED) | stem cell transplantation | NA | NA | NA | unclassified | |
after hla-matched allogeneic stem cell transplantation, beneficial anti-tumor immunity as well as detrimental side-effects can develop due to donor-derived t-cells recognizing polymorphic peptides that are presented by hla on patient cells. | |||||||
27618304 | HLA-CLASS I (HLA CLASS II) | stem cell transplantation | NA | NA | NA | only_studied | |
we investigated the value of online prediction algorithms for miha discovery and determined the in silico characteristics of 68 autosomal hla class i-restricted miha that have been identified as natural ligands by forward strategies in which t-cells from in vivo immune responses after allogeneic stem cell transplantation are used to identify the antigen. | |||||||
27819684 | HLA MISMATCHED (HLA-MISMATCHED) | stem cell transplantation | NA | tacrolimus | NA | unclassified | |
tacrolimus plus sirolimus with or without atg as gvhd prophylaxis in hla-mismatched unrelated donor allogeneic stem cell transplantation. | |||||||
27856159 | HUMAN LEUKOCYTE ANTIGEN (HUMAN LEUKOCYTE ANTIGEN) | stem cell transplantation | NA | NA | NA | only_studied | |
in addition, pgd can identify embryos that are human leukocyte antigen compatible with an existing sibling affected by a haemoglobinopathy to support a haematopoietic stem cell transplantation. | |||||||
27922202 | HLA (HLA) | stem cell transplantation | French | NA | NA | unclassified | |
haematopoietic stem cell transplantation-coordinating nurses (hsct-cns) play an important role in informing related donors (rds) and in organising human leucocyte antigen (hla) tests, pre-donation workup and stem cells collection. |
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