Copyright 2024
| PMID | Allele | Disease | Population | Drug Names | SNP | Class | Sentence |
|---|---|---|---|---|---|---|---|
| 26856406 | HLA-DQA1*01 | congenital toxoplasmosis | NA | NA | NA | unclassified | |
| as hla class ii molecules play a key role in the immune system regulation, the aim of this study was to investigate whether hla-dqa1/b1 alleles are associated with susceptibility or protection to congenital toxoplasmosis. | |||||||
| 26856406 | HLA-DQA1*01 | congenital toxoplasmosis | NA | NA | NA | unclassified | |
| in the present study, a discriminatory potential of hla-dqa1/b1 alleles to identify susceptibility to congenital toxoplasmosis and the most severe cases has been shown. | |||||||
| 26672749 | HLA-B (HLA-B) | ocular toxoplasmosis | NA | NA | rs1051792 | unclassified | |
| mhc class i chain-related gene a polymorphisms and linkage disequilibrium with hla-b and hla-c alleles in ocular toxoplasmosis. | |||||||
| 26672749 | HLA-C (HLA-C) | ocular toxoplasmosis | NA | NA | rs1051792 | unclassified | |
| mhc class i chain-related gene a polymorphisms and linkage disequilibrium with hla-b and hla-c alleles in ocular toxoplasmosis. | |||||||
| 26672749 | MICA*00 | ocular toxoplasmosis | NA | NA | rs1051792 | positive+negation | |
| although the mica*002~hla-b*35 haplotype was associated with increased risk of developing ocular toxoplasmosis (p-value = 0.04; or = 2.20; 95% ci = 1.05-4.60), and the mica*008~hla-c*07 haplotype was associated with protection against the development of manifestations of ocular toxoplasmosis (p-value = 0.009; or: 0.44; 95% ci: 0.22-0.76), these associations were not statistically significant after adjusting for multiple comparisons. | |||||||
| 26672749 | HLA-C*07 | ocular toxoplasmosis | NA | NA | rs1051792 | positive+negation | |
| although the mica*002~hla-b*35 haplotype was associated with increased risk of developing ocular toxoplasmosis (p-value = 0.04; or = 2.20; 95% ci = 1.05-4.60), and the mica*008~hla-c*07 haplotype was associated with protection against the development of manifestations of ocular toxoplasmosis (p-value = 0.009; or: 0.44; 95% ci: 0.22-0.76), these associations were not statistically significant after adjusting for multiple comparisons. | |||||||
| 26672749 | MICA*00 | ocular toxoplasmosis | NA | NA | rs1051792 | positive+negation | |
| although the mica*002~hla-b*35 haplotype was associated with increased risk of developing ocular toxoplasmosis (p-value = 0.04; or = 2.20; 95% ci = 1.05-4.60), and the mica*008~hla-c*07 haplotype was associated with protection against the development of manifestations of ocular toxoplasmosis (p-value = 0.009; or: 0.44; 95% ci: 0.22-0.76), these associations were not statistically significant after adjusting for multiple comparisons. | |||||||
| 26672749 | HLA-B*35 | ocular toxoplasmosis | NA | NA | rs1051792 | positive+negation | |
| although the mica*002~hla-b*35 haplotype was associated with increased risk of developing ocular toxoplasmosis (p-value = 0.04; or = 2.20; 95% ci = 1.05-4.60), and the mica*008~hla-c*07 haplotype was associated with protection against the development of manifestations of ocular toxoplasmosis (p-value = 0.009; or: 0.44; 95% ci: 0.22-0.76), these associations were not statistically significant after adjusting for multiple comparisons. | |||||||
| 27827450 | HLA-CLASS I (HLA CLASS II) | ocular toxoplasmosis | NA | NA | NA | unclassified | |
| ocular toxoplasmosis: susceptibility in respect to the genes encoding the kir receptors and their hla class i ligands. | |||||||
| 27827450 | HLA (HLA) | ocular toxoplasmosis | NA | NA | NA | unclassified | |
| the objective of this study was to investigate the influence of the genes encoding the kir receptors and their hla ligands in the susceptibility of ocular toxoplasmosis. | |||||||
Copyright 2024