Copyright 2024
| PMID | Allele | Disease | Population | Drug Names | SNP | Class | Sentence |
|---|---|---|---|---|---|---|---|
| 7522686 | HLA-DRB1*10 | food allergy | NA | NA | NA | unclassified | |
| an analog peptide of the ova 323-339 which is known to strongly bind to i-ad partially inhibited the response of the tcl to ova 323-339 presented by hla-dr10, raising the possibility of peptide-based immunotherapy of food allergy. | |||||||
| 16802776 | HLA-CLASS II (HLA CLASS II) | food allergy | NA | NA | NA | unclassified | |
| peanut allergy is a common and severe phenotype of food allergy with a strong genetic component | |||||||
| 16802776 | HLA-CLASS II (HLA CLASS II) | peanut allergy | NA | NA | NA | unclassified | |
| peanut allergy is a common and severe phenotype of food allergy with a strong genetic component | |||||||
| 16802776 | HLA-CLASS II (HLA CLASS II) | peanut allergy | NA | NA | NA | unclassified | |
| lack of association of hla class ii alleles with peanut allergy. | |||||||
| 16802776 | HLA-CLASS II (HLA CLASS II) | peanut allergy | NA | NA | NA | unclassified | |
| to determine possible genotypic associations of hla class ii with peanut allergy and attempt replication of previously reported associations. | |||||||
| 16802776 | NA (NA) | peanut allergy | NA | NA | NA | unclassified | |
| sibling pairs discordant for peanut allergy were genotyped (low resolution) by polymerase chain reaction-based methods to 7 dq and 18 dr allele groups. | |||||||
| 16802776 | HLA-DR (HLA-DR) | peanut allergy | NA | NA | NA | unclassified | |
| sibling pairs discordant for peanut allergy were genotyped (low resolution) by polymerase chain reaction-based methods to 7 dq and 18 dr allele groups. | |||||||
| 16802776 | HLA-DQA1*03 | peanut allergy | NA | NA | NA | positive+negation | |
| distribution of dq7 (29% of children with peanut allergy vs 47% sibling controls) was statistically significantly different (p = .04) before statistical correction for multiple comparisons was made by multiplying them by the number of alleles tested (and not statistically significant after correction | |||||||
| 16802776 | HLA-DRB1*11 | peanut allergy | NA | NA | NA | positive | |
| distribution of dr11 was nearly statistically significant without statistical adjustment (26% with peanut allergy vs 41% of sibling controls | |||||||
| 16802776 | HLA-DRB1 (HLA-DRB1) | peanut allergy | NA | NA | NA | negation | |
| alleles that were previously reported to have a weak association with peanut allergy (drb1 *03, *08; dqb1 *0302, *04) were not verified in this cohort (unadjusted p > .44). | |||||||
Copyright 2024