Copyright 2024
| PMID | Allele | Disease | Population | Drug Names | SNP | Class | Sentence |
|---|---|---|---|---|---|---|---|
| 17665421 | HLA-B*27 | enteriti | NA | NA | NA | unclassified | |
| u937 monocytic cell transfectants stably expressing psv2neo resistant vector (mock), wild-type hla-b27, or mutated hla-b27 hcs with amino acid substitutions in the b pocket were differentiated, infected with s enteritidis, and treated with signaling pathway inhibitors or specific p38 small interfering rna (sirna). | |||||||
| 10505031 | HLA-CLASS I (HLA CLASS II) | colorectal cancers | NA | NA | NA | only_studied | |
| using flow cytometry, we studied the phenotype of tumour infiltrating lymphocytes (tils) in 41 enzymatically dissociated colorectal cancers and compared this to the expression of hla class i and ii and cd80 on tumour cells. | |||||||
| 27057447 | HLA-CLASS I (HLA CLASS II) | colorectal cancers | NA | NA | NA | unclassified | |
| between 30 and 40% of lynch syndrome-associated colorectal cancers display loss of hla class i antigen expression as a result of beta2-microglobulin (b2m) mutations. | |||||||
| 27057447 | HLA-CLASS I (HLA CLASS II) | lynch syndrome | NA | NA | NA | unclassified | |
| between 30 and 40% of lynch syndrome-associated colorectal cancers display loss of hla class i antigen expression as a result of beta2-microglobulin (b2m) mutations. | |||||||
| 31853669 | HLA-CLASS I (HLA CLASS II) | colorectal cancers | NA | NA | NA | unclassified | |
| one of the most common mechanisms of immune evasion in msi colorectal cancers (crcs) is loss of hla class i expression due to mutations in b2m gene which can become a negative predictor for checkpoint blockade therapy. | |||||||
| 21689134 | HLA-A (HLA-A) | male infertility | Chinese | NA | NA | unclassified | |
| some studies have reported hla-a gene to have a strong role in idiopathic male infertility in japanese and yugoslavia populations. | |||||||
| 21689134 | HLA-A (HLA-A) | male infertility | Chinese | NA | NA | only_studied | |
| prompted by these findings, we investigated the distributions of hla-a gene to ascertain their associations with idiopathic male infertility in chinese population. | |||||||
| 21689134 | HLA-A (HLA-A) | male infertility | Chinese | NA | NA | unclassified | |
| polymerase chain reaction-sequence-based typing (pcr-sbt) method was used for dna typing at hla-a locus in 109 patients with idiopathic male infertility and 152 healthy controls in han male population of shaanxi province, situated in north-western china. | |||||||
| 21689134 | HLA-A (HLA-A) | male infertility | Chinese | NA | NA | positive+negation | |
| however, no significant differences of these allelic frequencies were found between the patients and the control subjects, suggesting that the hla-a gene was unlikely a major risk factor of idiopathic male infertility in this sample population. | |||||||
| 21689134 | HLA (HLA) | male infertility | Chinese | NA | NA | unclassified | |
| as different populations have different hla polymorphisms, investigation into the relationship of other hla genes and idiopathic male infertility in our population is needed in the future. | |||||||
Copyright 2024