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| PMID | Allele | Disease | Population | Drug Names | SNP | Class | Sentence |
|---|---|---|---|---|---|---|---|
| 6768210 | HLA (HLA) | paroxysmal nocturnal hemoglobinuria | Cuban | NA | NA | unclassified | |
| hla antigens in paroxysmal nocturnal hemoglobinuria. | |||||||
| 11986222 | HLA-DR2 (BROAD ANTIGEN) | paroxysmal nocturnal hemoglobinuria | NA | cyclophosphamide | NA | positive | |
| in newly diagnosed aa, the average frequency of cdr3 size distribution deviation indicative of oligoclonal t-cell proliferation was increased (44% +/- 33% vs 9% +/- 9%; p =.0001); aa patients with human leukocyte antigen (hla)-dr2 and those with expanded paroxysmal nocturnal hemoglobinuria clones showed more skewed vb repertoires. | |||||||
| 11986222 | HUMAN LEUKOCYTE ANTIGEN (HUMAN LEUKOCYTE ANTIGEN) | paroxysmal nocturnal hemoglobinuria | NA | cyclophosphamide | NA | positive | |
| in newly diagnosed aa, the average frequency of cdr3 size distribution deviation indicative of oligoclonal t-cell proliferation was increased (44% +/- 33% vs 9% +/- 9%; p =.0001); aa patients with human leukocyte antigen (hla)-dr2 and those with expanded paroxysmal nocturnal hemoglobinuria clones showed more skewed vb repertoires. | |||||||
| 17195527 | HLA-DRB1 (HLA-DRB1) | paroxysmal nocturnal hemoglobinuria | NA | NA | NA | only_studied | |
| the clone of paroxysmal nocturnal hemoglobinuria (pnh) was identified in 7 of 33 patients (21%), antigen hla-drb1 *15 in 6 of 11 patients (55%). | |||||||
| 18396213 | HLA-A (HLA-A) | paroxysmal nocturnal hemoglobinuria | Italian | NA | NA | unclassified | |
| paroxysmal nocturnal hemoglobinuria: significant association with specific hla-a, -b, -c, and -dr alleles in an italian population. | |||||||
| 18396213 | HLA-DR (HLA-DR) | paroxysmal nocturnal hemoglobinuria | Italian | NA | NA | unclassified | |
| paroxysmal nocturnal hemoglobinuria: significant association with specific hla-a, -b, -c, and -dr alleles in an italian population. | |||||||
| 27263775 | HLA-DRB1 (HLA-DRB1) | paroxysmal nocturnal hemoglobinuria | NA | NA | NA | positive | |
| several markers, such as hla-drb1(*)1501 and an increase in the percentage of paroxysmal nocturnal hemoglobinuria (pnh) phenotype cells, have been shown to represent the immune pathophysiology of aa. | |||||||
| 30037803 | HLA-DRB1*15 | paroxysmal nocturnal hemoglobinuria | NA | prednisone | NA | negation | |
| age, transfusion dependence, presence of paroxysmal nocturnal hemoglobinuria or large granular lymphocyte clones, and hla dr15 positivity did not predict response to ist. | |||||||
| 30504346 | HLA-CLASS I (HLA CLASS II) | paroxysmal nocturnal hemoglobinuria | NA | NA | NA | unclassified | |
| nearly 40% of aa patients carry somatic mutations in the piga gene manifested as clonal populations of cells with the paroxysmal nocturnal hemoglobinuria phenotype, and 17% of aa patients have loss of hla class i alleles. | |||||||
| 32256799 | HLA-DR2 (BROAD ANTIGEN) | paroxysmal nocturnal hemoglobinuria | NA | NA | NA | only_studied | |
| the following factors were identified as predictors of unresponsiveness: age (>=60 years), sex, absolute neutrophil count, severity of the disease, paroxysmal nocturnal hemoglobinuria clone, human leukocyte antigen (hla)-dr2 and cytogenetic abnormalities (cas). | |||||||
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