PMID | Allele | Disease | Population | Drug Names | SNP | Class | Sentence |
---|---|---|---|---|---|---|---|
11701553 | HLA-DR (HLA-DR) | b cell lymphomas | NA | trastuzumab | NA | unclassified | |
dr. levy updates the experience with rituximab targeting cd20 on b cell lymphomas and reviews the antibodies to cd3, cd22, cd33, cd52, hla-dr beta chain and hla-d currently in or proposed for clinical trials, including radiolabelled antibodies. | |||||||
11701553 | HLA-DR (HLA-DR) | unstable angina | NA | trastuzumab | NA | unclassified | |
in the last section, dr. coller reviews the therapeutic results achieved with abciximab (reopro), an antagonist of platelet receptor gpiibiiia for the prevention of restenosis in percutaneous coronary interventions and the treatment of unstable angina. | |||||||
6387532 | HLA (HLA) | adrenoleukodystrophy | NA | NA | NA | unclassified | |
an allogeneic bone marrow transplant (bmt) from a normal hla identical sibling donor was performed in a 13-year-old boy with rapidly progressive adrenoleukodystrophy (ald). | |||||||
6391533 | HLA-DR (HLA-DR) | lymphocytoma | NA | NA | NA | negation | |
the t cells were predominantly t helper/inducer cells and in all patients the t cells expressed hla-dr. one patient diagnosed as lymphocytoma cutis differed from the other patients by having no detectable b cells. | |||||||
6394752 | HLA-DR (HLA-DR) | pemphigoid gestationis | NA | NA | NA | unclassified | |
abnormal expression of hla-dr antigen in the placenta of a patient with pemphigoid gestationis. | |||||||
6394752 | HLA-DR (HLA-DR) | pemphigoid gestationis | NA | NA | NA | unclassified | |
the villous stroma and fetal endothelium in chorionic villi adjacent to maternal decidua in a placenta of a woman suffering from pemphigoid gestationis were found to have abnormal expression of hla-dr antigen. | |||||||
8113038 | HLA-DRB1*04 | pemphigoid gestationis | NA | NA | NA | unclassified | |
several groups have reported an association of pemphigoid gestationis to alleles of the human leukocyte antigens; hla-b8 (class i) and hla-dr3 and hla-dr4 (class ii), encoded on the short arm of chromosome 6. | |||||||
8113038 | HLA-B*08 | pemphigoid gestationis | NA | NA | NA | unclassified | |
several groups have reported an association of pemphigoid gestationis to alleles of the human leukocyte antigens; hla-b8 (class i) and hla-dr3 and hla-dr4 (class ii), encoded on the short arm of chromosome 6. | |||||||
8113038 | HLA-DR3 (BROAD ANTIGEN) | pemphigoid gestationis | NA | NA | NA | unclassified | |
several groups have reported an association of pemphigoid gestationis to alleles of the human leukocyte antigens; hla-b8 (class i) and hla-dr3 and hla-dr4 (class ii), encoded on the short arm of chromosome 6. | |||||||
8113038 | HLA-G (HLA-G) | pemphigoid gestationis | NA | NA | NA | unclassified | |
the hormonal regulation at the level of gene expression, possibly including gene expression of non-classic hla class i molecules such as hla-g, may be a cofactor in the pathogenesis of pemphigoid gestationis. |
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