Copyright 2024
| PMID | Allele | Disease | Population | Drug Names | SNP | Class | Sentence |
|---|---|---|---|---|---|---|---|
| 21251204 | HLA-DRB1*11 | hemophilia a | NA | NA | NA | unclassified | |
| sthe aim of the present study was to identify t-cell epitopes in fviii and characterize t-cell responses in two unrelated hemophilia a subjects sharing f8-r593c and hla-drb1*1101 genotypes. | |||||||
| 21251204 | HLA (HLA) | hemophilia a | NA | NA | NA | unclassified | |
| hemophilia a patients with r593c missense substitutions and these hla haplotypes had an increased incidence of inhibitors in our cohorts, supporting a paradigm in which presentation of fviii epitopes containing the wild-type r593 influences inhibitor risk in this hemophilia a sub-population. | |||||||
| 24744621 | HLA-CLASS II (HLA CLASS II) | hemophilia a | Thai | NA | NA | unclassified | |
| the association between hla class ii alleles and the occurrence of factor viii inhibitor in thai patients with hemophilia a. | |||||||
| 24744621 | HLA-DRB1 (HLA-DRB1) | hemophilia a | Thai | NA | NA | unclassified | |
| this study aimed to investigate the association between hla class ii alleles and the occurrence of fviiiinhibitor in thai hemophilia a patients.material and the distribution of hla-drb1 alleles and dqb1 alleles in 57 thai hemophilia a patientsand 36 blood donors as controls was determined using the pcr sequence-specific primer (pcr-ssp) method, and theassociation between the occurrence of factor viii (fviii) inhibitor and the presence of certain hla class ii alleles wasinvestigated. | |||||||
| 24744621 | HLA-DQB1 (HLA-DQB1) | hemophilia a | Thai | NA | NA | unclassified | |
| this study aimed to investigate the association between hla class ii alleles and the occurrence of fviiiinhibitor in thai hemophilia a patients.material and the distribution of hla-drb1 alleles and dqb1 alleles in 57 thai hemophilia a patientsand 36 blood donors as controls was determined using the pcr sequence-specific primer (pcr-ssp) method, and theassociation between the occurrence of factor viii (fviii) inhibitor and the presence of certain hla class ii alleles wasinvestigated. | |||||||
| 24744621 | HLA-DRB1*15 | hemophilia a | Thai | NA | NA | positive | |
| the frequency of hla-drb1*15 was higher in the hemophilia a patients with and without fviii inhibitor,whereas that of drb1*14, drb1*07, and dqb1*02 was lower in the hemophilia a patients with fviii inhibitor, ascompared to controls. | |||||||
| 24744621 | HLA-DRB1*14 | hemophilia a | Thai | NA | NA | positive | |
| the frequency of hla-drb1*15 was higher in the hemophilia a patients with and without fviii inhibitor,whereas that of drb1*14, drb1*07, and dqb1*02 was lower in the hemophilia a patients with fviii inhibitor, ascompared to controls. | |||||||
| 24744621 | HLA-DQB1*02 | hemophilia a | Thai | NA | NA | positive | |
| the frequency of hla-drb1*15 was higher in the hemophilia a patients with and without fviii inhibitor,whereas that of drb1*14, drb1*07, and dqb1*02 was lower in the hemophilia a patients with fviii inhibitor, ascompared to controls. | |||||||
| 24744621 | HLA-DRB1*07 | hemophilia a | Thai | NA | NA | positive | |
| the frequency of hla-drb1*15 was higher in the hemophilia a patients with and without fviii inhibitor,whereas that of drb1*14, drb1*07, and dqb1*02 was lower in the hemophilia a patients with fviii inhibitor, ascompared to controls. | |||||||
| 24744621 | HLA-DRB1*15 | hemophilia a | Thai | NA | NA | positive | |
| the study's findings show that the drb1*15 allele might have contributed to the occurrence of inhibitorin the thai hemophilia a patients; however, additional research using larger samples and high-resolution drb1 typingis warranted. | |||||||
Copyright 2024